Pharmaceutical-grade NAD+ restoration

Advanced cellular support with Niagen Plus

Niagen™ IV and Niagen™ Shots are administered by licensed healthcare professionals at select premium clinics nationwide.
Offerings

In-clinic therapies

From comprehensive NAD+ restoration to cellular health maintenance. Each format is manufactured to pharmaceutical-grade standards and administered by licensed healthcare professionals.

Niagen IV

NAD+ restoration in a fraction of traditional IV time, backed by the first randomized, placebo-controlled pilot study of IV NR.¹

Niagen Shots

Intramuscular Niagen® injection therapy, administered by a licensed provider directly into the muscle for on-the-go service.

Optimizing your health starts with cellular NAD+

Niagen IV

Niagen IV delivers pharmaceutical-grade NR for measurable NAD+ elevation within hours² to restore the foundation your cellular optimization depends on.
Better Tolerability

Your comfort, prioritized

Traditional NAD+ IV protocols are known for discomfort that limits infusion rate and extends session time.

Niagen IV was developed for a different experience: peer-reviewed clinical data documents a tolerability profile with only minor, transient experiences during infusion.² ³

Faster infusion times

Your time, restored

A pilot study revealed that Niagen IV increases NAD+ levels more than 20% within 3 hours post-infusion, with 75% less infusion time than NAD+ IV.¹

Pharmaceutical-grade NAD+ restoration, designed to complement your schedule.³

Unmatched quality

Our standard, upheld

Two clinical studies. Controlled methodology.¹ Peer-reviewed, real-world confirmation.² No other NAD+-boosting IV carries the level of clinical documentation that Niagen® NR IV does including NAD+ IV itself.

Administered by licensed healthcare professionals, with peer-reviewed real-world data documenting tolerability over a 30 days follow-up period.² ³

Niagen Shots

Niagen Shots deliver pharmaceutical-grade Niagen® via intramuscular injection at select clinics nationwide. Administered in under 15 minutes by a licensed healthcare professional.³

Cellular support in minutes

Every Niagen Shots vial is compounded by a licensed 503B outsourcing facility operating under cGMP standards, with third-party verification of purity and potency.

Administered by a licensed healthcare professional at select clinics nationwide, with no extended sessions and no lengthy preparation.³

NAD+ SCIENCE IN PRACTICE
"What excites me most about Niagen IV therapy is that we're not chasing a quick fix. We're playing the long game for healthy aging and longevity. The data we're collecting on sleep, energy, and cognitive clarity is growing more compelling with every person we study".
— Dr. Rachele Pojednic, Chief Scientific Officer at Restore Hyper Wellness

Access Niagen Plus near you

Cellular health science meets world-class hospitality.

  • Pharmaceutical-grade therapy delivered with clinical oversight
  • The same precision Niagen® at every participating clinic
  • Available at 1200+ premium locations nationwide
  • Schedule a concierge clinical session for in-office or in-home therapy
DISCLAIMERS
  1. Hawkins J, Idoine R, Kwon J, Shao A, Dunne E, Hawkins E, Dawson K, Nkrumah-Elie Y. Randomized, placebo-controlled, pilot clinical study evaluating acute Niagen®+ IV and NAD+ IV in healthy adults. medRxiv. 2024. doi: 10.1101/2024.06.06.24308565. This study is a preprint and has not yet been peer-reviewed.
  2. Reyna K, Heinzen G, Patel N, Ritter M, Siojo A, Legere H, Pojednic R. Intravenous infusion of nicotinamide adenine dinucleotide (NAD+) versus nicotinamide riboside (NR): a retrospective tolerability pilot study in a real-world setting. Front Aging. 2026 Feb 2;7:1652582. doi: 10.3389/fragi.2026.1652582.
  3. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.