FAQs

Niagen Plus is a pharmaceutical-grade form of Niagen® (nicotinamide riboside chloride), designed for intravenous (IV) and injectable administration under medical supervision. Niagen® is patented nicotinamide riboside chloride (NRCl), a form of vitamin B3 that serves as a precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme essential for cellular energy production, repair, and supports metabolic resilience.¹

Tru Niagen® is a food-grade dietary supplement taken orally and available directly to consumers.

Niagen Plus is a pharmaceutical-grade, prescription-only formulation administered by a healthcare professional or under medical guidance, designed for intravenous or injectable administration.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell in the body and is essential for hundreds of biological processes including cellular energy metabolism and cellular health. NAD+ levels naturally decline with age and chronic exposure to metabolic stressors, which is one reason why strategies to support NAD+ production have gained significant scientific interest.

Niagen Plus delivers nicotinamide riboside (NR), a precursor molecule that cells use to produce NAD+. Niagen IV bypasses digestion for 100% bioavailability, providing NR that your cells can convert into NAD+ to support cellular energy and metabolic health.¹

Yes. Niagen Plus therapies require a prescription and must be administered or supervised by a licensed healthcare professional.

Niagen Plus treatments are administered by trained medical professionals in licensed clinics, or self-administered at home under prescription-only, clinician-directed guidance.

Healthcare providers may recommend Niagen Plus for individuals seeking cellular health support. A qualified medical professional will determine if treatment is appropriate for your individual health needs¹

Niagen® (nicotinamide riboside chloride), the active ingredient in Niagen Plus, has been evaluated in 40+ published human clinical studies in oral form, with documented tolerability.

For the IV formulation, a randomized, placebo-controlled pilot study² evaluated acute response, and a peer-reviewed retrospective tolerability study³ in a real-world clinical setting reported minor transient experiences and no clinically significant changes in liver enzymes or inflammatory markers at 30 days post-infusion.

Subcutaneous administration (Niagen® At-Home Injection Kit) has been clinically studied and shown to be safe and well-tolerated in human studies

Niagen Plus is prescription-only and administered or prescribed by licensed healthcare professionals.¹

You can locate authorized clinics and providers through the Niagen Plus Clinic Locator on the Niagen Plus website.

The Niagen At-Home Injection Kit provides a prescription formulation of Niagen®designed for subcutaneous injection outside of a clinic setting, under medical supervision and guidance from a licensed healthcare provider. Niagen Bioscience is not the manufacturer or compounder of this product. Compounding is performed by a licensed 503B outsourcing facility.

After purchasing the At-Home Injection Kit, patients will be prompted to complete a medical intake questionnaire. Once the questionnaire is complete it will be reviewed by a licensed physician who determines whether treatment is appropriate. If prescribed, the injection kit is shipped along with instructions and provided medical guidance for proper administration.

The Niagen At-Home Injection Kit is designed for subcutaneous administration — injections into the fatty tissue layer beneath the skin. Your licensed provider will determine the appropriate administration method. The most common injection site for subcutaneous injection is in the abdomen.

Medical supervision is provided through a licensed telehealth provider. Even though injections may be performed at home, the treatment requires a prescription and ongoing management by a licensed healthcare professional. If you have any questions regarding the treatment you can reach out to your provider by navigating to your account, then to your order. Within your order there is a chat button for you to communicate directly with the provider who approved your prescription.

No. While both deliver Niagen®, Niagen IV is administered intravenously in a clinical setting, while the at-home kit uses subcutaneous injections that can be administered outside the clinic, with medical guidance.

Dosage and frequency depend on the treatment plan established by your healthcare provider.

Individuals who are pregnant, breastfeeding, or managing certain medical conditions—including prior (or current) cancer diagnosis, liver disease, or kidney disease—should consult their healthcare provider before use. Children should not use Niagen Plus. Only a qualified medical professional can determine eligibility.

Availability varies by state. Some states have restrictions on the shipment of compounded prescription products. Eligibility will be confirmed as part of the telehealth consultation process. Currently, the Niagen At-Home Injection Kit is not available to ship to Alabama, Arkansas, and California.

• All purchases require completion of a medical intake form and physician review.
• Prescription approval is not guaranteed.
• If your prescription is not approved after medical review, you will receive a full refund within 7–10 business days.
• If you are found ineligible during the intake process, contact our support team and we will process your refund.
• If you do not complete your intake form within 30 days, your order will expire and you will be automatically refunded.
• Once a prescription has been approved and issued, the order is final and cannot be refunded or returned.

Are your clinicians licensed?

• Yes. All providers are licensed physicians practicing within your state.

Can you list your providers for Rhode Island and Vermont

• In accordance with the laws and regulations in Vermont and Rhode Island, you can click here for a list of providers prescribing for those states.

What about all other states?

• If you have questions about the providers in your state, please reach out. Our customer service team is happy to help.

Get in touch with us here.